Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 14; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Structural Analysis and Characterization of an Antiproliferative Lectin from Canavalia villosa Seeds.

Authors : Lossio CF; Laboratory of Biologically Active Molecules, Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza 60440-970, Brazil.; Osterne VJS

Subjects: Lectins*/Lectins*/Lectins*/pharmacology ; Lectins*/Lectins*/Lectins*/analysis ; Canavalia*/Canavalia*/Canavalia*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 04; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Crosstalk of Inflammation and Coagulation in Bothrops Snakebite Envenoming: Endogenous Signaling Pathways and Pathophysiology.

Authors : Cavalcante JS; Graduate Program in Tropical Diseases, Botucatu Medical School (FMB), São Paulo State University (UNESP-Univ Estadual Paulista), Botucatu 18618-687, São Paulo, Brazil.; de Almeida DEG

Subjects: Snake Bites*/Snake Bites*/Snake Bites*/complications ; Bothrops*; Humans

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 15; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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USP15-USP7 Axis and UBE2T Differential Expression May Predict Pathogenesis and Poor Prognosis in De Novo Myelodysplastic Neoplasm.

Authors : de Carvalho LGA; Center for Research and Drug Development (NPDM), Federal University of Ceara, Fortaleza 60020-181, CE, Brazil.; Post-Graduate Program in Translational Medicine, Federal University of Ceara, Fortaleza 60020-181, CE, Brazil.

Subjects: Neoplasms* ; Myelodysplastic Syndromes*/Myelodysplastic Syndromes*/Myelodysplastic Syndromes*/pathology; Humans

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 13; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Immobilization of Lipase B from Candida antarctica in Octyl-Vinyl Sulfone Agarose: Effect of the Enzyme-Support Interactions on Enzyme Activity, Specificity, Structure and Inactivation Pathway.

Authors : Souza PMP; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Food Engineering Department, Federal University of Ceará, Campus do Pici, Bloco 858, Fortaleza CEP 60440-900, CE, Brazil.

Subjects: Lipase*/Lipase*/Lipase*/metabolism ; Enzymes, Immobilized*/Enzymes, Immobilized*/Enzymes, Immobilized*/chemistry; Sepharose/Sepharose/Sepharose/chemistry Moesziomyces antarcticus

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 17; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Chronic Methylmercury Intoxication Induces Systemic Inflammation, Behavioral, and Hippocampal Amino Acid Changes in C57BL6J Adult Mice.

Authors : Nascimento TS; Neuroscience and Behavior Laboratory, Drug Research and Development Center, Federal University of Ceará, Fortaleza 60430-275, Brazil.; Pinto DV

Subjects: Methylmercury Compounds*/Methylmercury Compounds*/Methylmercury Compounds*/toxicity ; Methylmercury Compounds*/Methylmercury Compounds*/Methylmercury Compounds*/metabolism; Animals

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 10; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Quantum Biochemistry and MM-PBSA Description of the ZIKV NS2B-NS3 Protease: Insights into the Binding Interactions beyond the Catalytic Triad Pocket.

Authors : de Paula Junior VF; Biotechnology & Molecular Biology Laboratory, State University of Ceará, Fortaleza 60714-903, Brazil.; van Tilburg MF

Subjects: Zika Virus*/Zika Virus*/Zika Virus*/metabolism ; Zika Virus Infection*; Molecular Dynamics Simulation

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 03; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Molecular Dynamics of CYFIP2 Protein and Its R87C Variant Related to Early Infantile Epileptic Encephalopathy.

Authors : Biembengut ÍV; Laboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Fundação Oswaldo Cruz Paraná (Fiocruz-PR), Curitiba 80320-290, Brazil.; Shigunov P

Subjects: Molecular Dynamics Simulation* ; Spasms, Infantile*/Spasms, Infantile*/Spasms, Infantile*/genetics; Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/metabolism Infantile Epileptic-Dyskinetic Encephalopathy

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Aug 05; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Circadian Rhythm Dysregulation and Leukemia Development: The Role of Clock Genes as Promising Biomarkers.

Authors : Sanford ABA; Unichristus University Center, Faculty of Biomedicine, Fortaleza 60430-275, CE, Brazil.; da Cunha LS

Subjects: Chronobiology Disorders* ; Circadian Clocks*/Circadian Clocks*/Circadian Clocks*/genetics ; Leukemia*/Leukemia*/Leukemia*/genetics

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 26; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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1,4-Naphthoquinone (CNN1) Induces Apoptosis through DNA Damage and Promotes Upregulation of H2AFX in Leukemia Multidrug Resistant Cell Line.

Authors : de Sousa Portilho AJ; Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.; da Silva EL

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 23; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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